The son of Exceed And Excel (Danehill) was relocated last month from Chatswood Stud to Larneuk Stud, but was withdrawn from service due to an existing foot abscess.
"This really is tragic," Larneuk Stud's Neville Murdoch points out.
"All of us at the farm and the shareholders in the horse are absolutely devastated … he (Reward For Effort) really made an impression with us from the short time he was on farm and it's also a tremendous blow to Victoria's breeding industry. Not only has he produced a lot of winners, I'm absolutely convinced the best was yet to come."
Reward For Effort has sired eight stakes winners to date including the Group winning quartet Gold Symphony, Ability, Take Pride and Brugal Reward. He covered a book of 105 mares last season.